Most external input comes from the adjoining entorhinal cortex, via the axons of the so-called perforant path. The major pathways of signal flow through the hippocampus combine to form a loop. To refer to the hippocampus proper plus dentate gyrus and subiculum. Use the term "hippocampus proper" to refer to the four CA fields, and "hippocampal formation" Transition to the cortex proper (mostly the entorhinal area of the cortex). After this come a pair of ill-defined areas called the presubiculum and parasubiculum, then a After CA1 comes an area called the subiculum. The CA areas are all filled with densely packed pyramidal cells resembling those of the cortex. NextĬome a series of Cornu Ammonis areas: first CA4 (which underlies the dentate gyrus), then CA3, thenĪ very small zone called CA2, then CA1. ![]() Proper, forming a pointed wedge in some cross-sections, a semicircle in others. Structure, a tightly packed layer of small granule cells wrapped around the end of the hippocampus The first of these, the dentate gyrus (DG), is actually a separate ![]() Starting at the dentate gyrus and working inward along the S-curve of the hippocampus means traversing a Basic circuit of the hippocampus, shown using a modified drawing by Ramon y Cajal.
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